Arthritis describes a loss of cartilage from a joint resulting in pain, stiffness and a loss of function. Commonly it is described as “osteoarthritis” when attributed to wear and tear. It can be caused by inflammatory conditions such as rheumatoid arthritis or following injury or infection. Patients typically describe an aching type of knee pain, aggravated by activity and often worse in the evening. It may affect one, two, or all three of the compartments of the knee.